导读:英语翻译Our combined results strongly support a role for the mic 英语翻译Our combined results strongly support a role for the microtubule cytoskeleton in targeting CSC secretion.CSC density and cort...
英语翻译Our combined results strongly support a role for the mic
英语翻译
Our combined results strongly support a role for the microtubule cytoskeleton in targeting CSC secretion.CSC density and cortical microtubule density are correlated during cellular differentiation in the hypocotyl (Figure 2),suggesting that cortical microtubules may be involved in regulating CSC delivery to the plasma membrane.Wedemonstrate that newCSC insertions are preceded by pauses of the Golgi apparatus at specific sites beneath the plasma membrane (Figures 5A to 5C).The so-called stop-and-go behavior of Golgi bodies was proposed to be due to pauses at ER export sites (Nebenfu¨ hr et al.,1999); however,recent evidence suggests that ER export sites and Golgi stacks may form mobile secretory units (daSilva et al.,2004).Our data reveal that Golgi bodies pause at cortical microtubules,and these pauses often result in insertion of CSCs at the plasma membrane (Figures 5A to 5C).
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我们的综合结果有力地支持在把SCS分泌物作为目标的微管细胞骨架而起到的作用.CSC 密度和皮层微管密度在胚轴中细胞变异期间是相互依从的(图2),间接表明皮层微管可能与把CSC转移调节到原生质膜有关.我们证明新CSC的嵌入在原生质膜下面的特定处出现在高尔基体停顿的前面(图5A到5C).所谓的高尔基体的断续性行为认为是由于位于ER导出点位的停顿所致(尼本夫等人,1999年),不过近期的迹象表明ER导出点位和高尔基堆会形成分泌组(德思尔瓦等,2004年).我们的数据显示了高尔基体在皮质微管停顿,这些停顿总是在质膜处导致一些CSC的嵌入(图5A到5C).
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